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  • October 31, 2024

STX-003: Utilizing Programmable Genetic Circuits for Tumor-Specific IL-12 Expression and Reduced Toxicity with Systemically Delivered mRNA

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  • May 10, 2024

Circular RNA Based Chimeric Antigen Receptor (CAR) Cell Therapy for Potent and Long-Lasting Anti-Tumor Activity

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  • May 10, 2024

STX-003: A Novel Systemically-Delivered mRNA-Based Cancer Therapy Utilizing a Programmable Genetic Circuit Platform for Tumor-Specific Protein Expression and Reduced Toxicity

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  • April 17, 2023

2731 / 2 – STX-001, a locally administered LNP-formulated self-replicating mRNA that encodes the therapeutic payload IL-12, induces deep systemic immune responses to solid tumors

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  • September 19, 2020

Pseudovirus
for immunotherapy

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  • August 10, 2020

Multifunctional oncolytic nanoparticles deliver self-replicating IL-12 RNA to eliminate established tumors and prime systemic immunity

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  • August 3, 2019

Mammalian synthetic circuits with RNA binding proteins for RNA-only delivery

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  • October 16, 2018

Small-molecule-based regulation of RNA-delivered circuits in mammalian cells

»

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